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Furosemide sodium

CAS No. 41733-55-5

Furosemide sodium( —— )

Catalog No. M34751 CAS No. 41733-55-5

Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Furosemide sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2.
  • Description
    Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl-?(NKCC) cotransporter, NKCC1 and NKCC2.?Furosemide sodium is also a GABAA?receptors antagonist and displays 100-fold selectivity for?α6-containing receptors than?α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GABA Receptor | Na-K-Cl cotransporter
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    41733-55-5
  • Formula Weight
    352.73
  • Molecular Formula
    C12H10ClN2NaO5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 150 mg/mL (425.25 mM; )H2O : 100 mg/mL (283.50 mM; Ultrasonic)
  • SMILES
    O=C([O-])C1=CC(S(=O)(N)=O)=C(Cl)C=C1NCC2=CC=CO2.[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. C M Gillen, et al. Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family. J Biol Chem. 1996 Jul 5;271(27):16237-44.?
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